About Us

Welcome to the Systems Biology Laboratory located at the Faculty of Informatics of Masaryk University in Brno. The laboratory was established in 2009 with the aim of integrating and intensifying research and education activities in the emerging area of Digital Systems Biology at the Faculty of Informatics, Masaryk University.

From January 1, 2016 we became part of the national research infrastructure C4Sys (Centre for System Biology), representing a Czech node of the ISBE (Infrastructure for Systems Biology – Europe), and our activities are supported from the program for large research infrastructures of the Ministry of Education, Youth and Sports.


To understand complex biological systems requires the integration of experimental and computational research – in other words a systems biology approach. (Kitano, 2002)

Current challenges in computational systems biology call for new insights coming from computer science, especially, the field of formal methods. This is motivated by the need for model-based computational analysis and exploration of hardly-predictable behaviour emerging from complex dynamical systems.

Our long-term research goal is to develop and apply computational science and technology to enhance our understanding of the molecular mechanisms underlying the behaviour of living systems and develop scalable methods and tools for modelling and computerised analysis of large and complex dynamical systems.

Our another goal is to support education in Systems biology by offering a challenging multi-disciplinary working environment for students aspiring to be in the forefront of modern computational biology.

Prof. Luboš Brim
Head of the Laboratory